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Acrylamide (AA) is predominantly used as a synthetic substance within various industries. However, AA is also recognized as a carcinogen. Zinc oxide nanoparticles (ZnO-NPs) are becoming increasingly attractive as medical agents. However, to the knowledge, the effects of ZnO-NPs on preventing cytotoxicity with AA have not been reported. Therefore, this study aims to determine the protective effects of ZnO-NPs against the cytotoxicity caused by AA.

MTT assay was used to determine the cytotoxicity. Reactive oxygen species (ROS) formation, carbonyl protein, malondialdehyde (MDA) and glutathione (GSH) were measured and analyzed statistically.

The findings observed that the presence of 200 µM AA led to a substantial reduction in cell viability (p < 0.001). However, ZnO-NPs restored cell viability at 50 and 100 µM concentrations (p = 0.0121 and p = 0.0011, respectively). The levels of ROS were significantly reduced (p = 0.001 and p = < 0.001) to 518 ± 47.57 and 364 ± 47.79, respectively, compared to the AA group. The levels of GSH were significantly increased (p = 0.004 and p = 0.002) to 16.9 ± 1.3 and 17.6 ± 0.5, respectively, compared to the AA group. The levels of MDA were significantly decreased (p = 0.005, p < 0.001 and p < 0.001) when compared to the AA group, as were the levels of carbonyl protein (p = 0.009 and p < 0.002) in comparison to the AA group.

In summary, the outcomes of this research indicate that ZnO-NPs played a role in inhibiting AA-induced oxidative stress and cytotoxicity.

Finding the optimal maintenance schedules is the primitive aim of preventive maintenance scheduling (PMS) problem dealing with the objectives of reliability, risk and cost. Most of the earlier works in the literature have focused on PMS with the objectives of leveling reserves/risk/cost independently. Nevertheless, very few publications in the current literature tackle the multi-objective PMS model with simultaneous optimization of reliability, and economic perspectives. Since, the PMS problem is highly nonlinear and complex in nature, an appropriate optimization technique is necessary to solve the problem in hand. The paper aims to discuss these issues.

The complexity of the PMS problem in power systems necessitates a simple and robust optimization tool. This paper employs the modern meta-heuristic algorithm, namely, Ant Lion Optimizer (ALO) to obtain the optimal maintenance schedules for the PMS problem. In order to extract best compromise solution in the multi-objective solution space (reliability, risk and cost), a fuzzy decision-making mechanism is incorporated with ALO (FDMALO) for solving PMS.

As a first attempt, the best feasible maintenance schedules are obtained for PMS problem using FDMALO in the multi-objective solution space. The statistical measures are computed for the test systems which are compared with various meta-heuristic algorithms. The applicability of the algorithm for PMS problem is validated through statistical t-test. The statistical comparison and the t-test results reveal the superiority of ALO in achieving improved solution quality. The numerical and statistical results are encouraging and indicate the viability of the proposed ALO technique.

As a maiden attempt, FDMALO is used to solve the multi-objective PMS problem. This paper fills the gap in the literature by solving the PMS problem in the multi-objective framework, with the improved quality of the statistical indices.

The purpose of this paper is to solve the realistic problem of source maintenance scheduling (SMS) based on reliability criterion. A novel effective optimization technique is proposed to solve the problem at hand.

The problem has been formulated as a combinatorial optimization task, with the goal of maximizing reliability by minimizing the sum of squares of the reserve loads while satisfying unit and system constraints. This paper employs a nature inspired algorithm known as Teaching Learning Based Optimization (TLBO) for solving the SMS problem based on reliability.

The results reveal that optimal maintenance schedules of generating units has been obtained using TLBO algorithm with minimized values of sum of squares of reserve loads while satisfying system and operational constraints. It is also found that the inclusion of resource constraints (RC) in the model have significant effects on the objective function value which provides a deep insight of the proposed methodology.

The contribution of this paper is that an efficient nature inspired algorithm has been applied to solve source maintenance scheduling problem in viewpoint of the planning for future system capacity expansion. The incorporation of exclusion and RC in the model makes the analysis about the impact of SMS on the system reliability more reasonable.

Generator maintenance scheduling (GMS) is an essential task for electric power utilities as the periodical maintenance activity enhances the lifetime and also ensures the reliable and continuous operation of generating units. Though numerous meta-heuristic algorithms have been reported for the GMS solution, enhancing the existing techniques or developing new optimization procedure is still an interesting research task. The meta-heuristic algorithms are population based and the selection of their algorithmic parameters influences the quality of the solution. This paper aims to propose statistical tests guided meta-heuristic algorithm for solving the GMS problems.

The intricacy characteristics of the GMS problem in power systems necessitate an efficient and robust optimization tool. Though several meta-heuristic algorithms have been applied to solve the chosen power system operational problem, tuning of their control parameters is a protracting process. To prevail over the previously mentioned drawback, the modern meta-heuristic algorithm, namely, ant lion optimizer (ALO), is chosen as the optimization tool for solving the GMS problem.

The meta-heuristic algorithms are population based and require proper selection of algorithmic parameters. In this work, the ANOVA (analysis of variance) tool is proposed for selecting the most feasible decisive parameters in algorithm domain, and the statistical tests-based validation of solution quality is described. The parametric and non-parametric statistical tests are also performed to validate the selection of ALO against the various competing algorithms. The numerical and statistical results confirm that ALO is a promising tool for solving the GMS problems.

As a first attempt, ALO is applied to solve the GMS problem. Moreover, the ANOVA-based parameter selection is proposed and the statistical tests such as Wilcoxon signed rank and one-way ANOVA are conducted to validate the applicability of the intended optimization tool. The contribution of the paper can be summarized in two folds: the ANOVA-based ALO for GMS applications and statistical tests-based performance evaluation of intended algorithm.

In recent years, instant messaging platforms like WhatsApp have gained substantial popularity in both academic and practical domains. However, despite this growth, there is a lack of a comprehensive overview of the literature in this field. The primary purpose of this study is to bridge this gap by analyzing a substantial dataset of 12,947 articles retrieved from the Dimensions.ai, database spanning from 2011 to March 2023.

To achieve the authors' objective, the authors employ bibliometric analysis techniques. The authors delve into various bibliometric networks, including citation networks, co-citation networks, collaboration networks, keywords and bibliographic couplings. These methods allow for the uncovering of the social and conceptual structures within the academic discourse surrounding WhatsApp.

The authors' analysis reveals several significant findings. Firstly, the authors observe a remarkable and continuous growth in the number of academic studies dedicated to WhatsApp over time. Notably, two prevalent themes emerge: the impact of coronavirus disease 2019 (COVID-19) and the role of WhatsApp in the realm of social media. Furthermore, the authors' study highlights diverse applications of WhatsApp, including its utilization in education and learning, as a communication tool, in medical education, cyberpsychology, security, psychology and behavioral learning.

This paper contributes to the field by offering a comprehensive overview of the scholarly research landscape related to WhatsApp. The findings not only illuminate the burgeoning interest in WhatsApp among researchers but also provide insights into the diverse domains where WhatsApp is making an impact. The analysis of bibliometric networks offers a unique perspective on the social and conceptual structures within this field, shedding light on emerging trends and influential research. This study thus serves as a valuable resource for scholars, practitioners and policymakers seeking to navigate the evolving landscape of WhatsApp research. The study will also be useful for researchers interested in conducting bibliometric analysis using Dimensions.ai, a free database.