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Nigeria, like any other country in the world, was overtaken by the coronavirus, a global pandemic that started as a local problem in China. The pandemic had a complex outlook, coming with threat to health and graduated to threat to the governance of the world community in all respects, including economy, social life and even politics. The threat to global health was a threat to which all nations have to respond, even when the infection level was quite low. The federal government in Nigeria responded in many ways in order to contain the pandemic. The federal government responded to the pandemic through presidential actions, institutional measure and support systems in order to contain the spread of the pandemic. These governance instruments have different outcomes in terms of the limitation of the spread of the pandemic, perception of the pandemic, changing attitudes in order to live with the pandemic and building resilience among the population. The objectives of this chapter are to trace the dynamics of the coronavirus pandemic in Nigeria, examine the executive actions to contain the pandemic, examine the institutional and legal instruments for the containment of the pandemic, to assess the medical management responses of the pandemic, relate the governance process to the outcome of the pandemic and draw lessons for the governance of future health disaster.